Komputerowy model symulacyjny zabiegu bronchoskopii oraz jego zastosowanie do opracowania i testowania metod estymacji przesunięcia końcówki bronchofiberoskopu

Promotor: Tomasz P. Zieliński.Recenzent: Ryszard Tadeusiewicz, Michał Strzelecki.Niepublikowana praca doktorska.Tyt. z ekranu tyt.Praca doktorska. Akademia Górniczo-Hutnicza im. Stanisława Staszica (Kraków), 2013.Zawiera bibliogr.Dostępna również w wersji drukowanej.Tryb dostępu: Internet.Aktualny stan wiedzy medycznej i technicznej, układ oddechowy człowieka, budowa tchawicy i oskrzeli, węzły chłonne, rozmieszczenie węzłów chłonnych w klatce piersiowej, bronchoskopia, tomografia komputerowa, zasada działania tomografii komputerowej interpretacja danych, wspomaganie zabiegów, model zabiegu bronchofiberoskopii, wirtualna bronchoskopia, model wirtualnego fantomu drzewa oskrzelowego, modelowanie kształtu, szkielet drzewa oskrzelowego, dodanie szczegółów, pogrubienie szkieletu, rekonstrukcja powierzchni, modelowanie wyglądu powierzchni, model cieniowania, mapowanie tekstur, model kamery endoskopu, dystorsja obrazu, identyfikacja parametrów modelu zniekształceń, implementacja wirtualnego modelu kamery, model oświetlenia endoskopu, metoda śledzenia końcówki bronchofiberoskopu, przegląd metod, opracowana metoda śledzenia bronchoskopu, analiza ruchu kamery, szacowanie przesunięcia endoskopu, wyznaczanie ruchu endoskopu, koszty obliczeniowe algorytmu, korelacja, dokładne dopasowywanie obrazów metodą informacji wzajemnej, weryfikacja metody, akceleracja obliczeń w technologii CUDA, przygotowanie danych, korelacja obrazów, analiza wydajności, zagadnienia informatyczne, biblioteka VTK, architektura, strumień wizualizacji, model graficzny, podstawowe obiekty modelu graficznego VTK, reprezentacja danych, typy atrybutów danych, typy zbiorów danych, biblioteka CUDA, przetwarzanie danych w GPU, organizacja pamięci, interfejs programist

Metoda wyznaczania współczynnika tarcia kinetycznego par ciernych w oparciu o bezpośredni pomiar przyspieszenia obiektu na równi pochyłej

The paper presents and experimentally verifies a method for the determination of the kinetic friction coefficient of friction pairs. The method involves a direct acceleration measurement of an object sliding down an inclined plane and the determination of the momentary friction force based on acceleration. The laboratory test rig was presented and the theoretical foundations of the method were discussed in detail. The laboratory experiments were conducted for the following material pairs: steel-cast iron, steel-bronze, and for various inclined plane angles. The experiments results were presented, acceleration vs. time curves were plotted, and friction coefficients were determined. These values were compared to the values known from literature [L. 1–3]. The uncertainly analysis of kinetic friction coefficient determination was conducted. The method effectiveness and accuracy was verified, noting the sources of possible measurement errors and the ways to eliminate them.W artykule zaproponowano oraz eksperymentalnie zweryfikowano metodę wyznaczania współczynnika tarcia kinetycznego skojarzeń ciernych. Zastosowano metodę bezpośredniego pomiaru przyspieszenia obiektu zsuwającego się po równi pochyłej oraz wyznaczanie na podstawie przyspieszenia chwilowej wartości siły tarcia. Przedstawiono budowę stanowiska laboratoryjnego oraz szczegółowo omówiono podstawy teoretyczne metody. Badania laboratoryjne przeprowadzono dla następujących skojarzeń materiałów: stal–żeliwo, stal–brąz oraz dla różnej wartości kąta równi pochyłej. Zaprezentowano uzyskane wyniki eksperymentów, przebiegi czasowe mierzonych wartości przyspieszeń oraz wartości wyznaczonych współczynników tarcia. Wartości te porównano ze znanymi wartościami z literatury [L. 1–3]. Przeprowadzono analizę niepewności wyznaczania współczynnika tarcia kinetycznego. Potwierdzono skuteczność i dokładność metody, zwracając uwagę na źródła możliwych błędów pomiaru oraz możliwość ich eliminacji

Animal coronaviruses in the light of COVID-19

Coronaviruses are extremely susceptible to genetic changes due to the characteristic features of the genome structure, life cycle and environmental pressure. Their remarkable variability means that they can infect many different species of animals and cause different disease symptoms. Moreover, in some situations, coronaviruses might be transmitted across species. Although they are commonly found in farm, companion and wild animals, causing clinical and sometimes serious signs resulting in significant economic losses, not all of them have been classified by the World Organization for Animal Health (OIE) as hazardous and included on the list of notifiable diseases. Currently, only three diseases caused by coronaviruses are on the OIE list of notifiable terrestrial and aquatic animal diseases. However, none of these three entails any administrative measures. The emergence of the SARS-CoV-2 infections that have caused the COVID-19 pandemic in humans has proved that the occurrence and variability of coronaviruses is highly underestimated in the animal reservoir and reminded us of the critical importance of the One Health approach. Therefore, domestic and wild animals should be intensively monitored, both to broaden our knowledge of the viruses circulating among them and to understand the mechanisms of the emergence of viruses of relevance to animal and human health

Vitamin D Supplementation Guidelines for General Population and Groups at Risk of Vitamin D Deficiency in Poland—Recommendations of the Polish Society of Pediatric Endocrinology and Diabetes and the Expert Panel With Participation of National Specialist Consultants and Representatives of Scientific Societies—2018 Update

IntroductionVitamin D deficiency is an important public health problem worldwide. Vitamin D deficiency confers a significant risk for both skeletal and non-skeletal disorders and a number of lifelong negative health outcomes. The objectives of this evidence-based guidelines document are to provide health care professionals in Poland, an updated recommendation for the prevention, diagnosis and treatment of vitamin D deficiency.MethodsA systematic literature search examining the prevention and treatment strategies for vitamin D deficiency was conducted. Updated recommendations were developed using the Grading of Recommendations, Assessment, Development and Evaluation system describing the strength of the recommendation and the quality of supporting evidence. Twenty-seven contributors representing different areas of expertise and medical specialties, including pediatricians, geriatricians, endocrinologists, epidemiologists, nephrologists, gynecologists and obstetricians evaluated the available published evidence related to vitamin D, formulated the goals of this document and developed a common consolidated position. The consensus group, representing six national specialist consultants and eight Polish and international scientific organizations/societies, participated in the process of grading evidence and drawing up the general and specific recommendations.ResultsThe updated recommendations define the diagnostic criteria for the evaluation of vitamin D status and describe the prevention and treatment strategies of vitamin D deficiency in the general population and in groups at increased risk of the deficiency. Age- and weight-specific recommendations for prevention, supplementation and treatment of vitamin D deficiency are presented, and detailed practice guidance is discussed regarding the management in primary and specialized health care.ConclusionVitamin D deficiency remains still highly prevalent in Poland, in all age groups. Currently, there is a great necessity to implement a regular supplementation with recommended doses and to develop an effective strategy to alleviate vitamin D deficiency in the population. These updated recommendations are addressed to health professionals and the authorities pursuing comprehensive health policies and should also be included in public health programs aimed at preventing a broad spectrum of chronic diseases

Metabolic syndrome is associated with similar long-term prognosis in non-obese and obese patients. An analysis of 45 615 patients from the nationwide LIPIDOGRAM 2004-2015 cohort studies

Aims We aimed to evaluate the association between metabolic syndrome (MetS) and long-term all-cause mortality. Methods The LIPIDOGRAM studies were carried out in the primary care in Poland in 2004, 2006 and 2015. MetS was diagnosed based on the National Cholesterol Education Program, Adult Treatment Panel III (NCEP/ATP III) and Joint Interim Statement (JIS) criteria. The cohort was divided into four groups: non-obese patients without MetS, obese patients without MetS, non-obese patients with MetS and obese patients with MetS. Differences in all-cause mortality was analyzed using Kaplan-Meier and Cox regression analyses. Results 45,615 participants were enrolled (mean age 56.3, standard deviation: 11.8 years; 61.7% female). MetS was diagnosed in 14,202 (31%) by NCEP/ATP III criteria, and 17,216 (37.7%) by JIS criteria. Follow-up was available for 44,620 (97.8%, median duration 15.3 years) patients. MetS was associated with increased mortality risk among the obese (hazard ratio, HR: 1.88 [95% CI, 1.79-1.99] and HR: 1.93 [95% CI 1.82-2.04], according to NCEP/ATP III and JIS criteria, respectively) and non-obese individuals (HR: 2.11 [95% CI 1.85-2.40] and 1.7 [95% CI, 1.56-1.85] according to NCEP/ATP III and JIS criteria respectively). Obese patients without MetS had a higher mortality risk than non-obese patients without MetS (HR: 1.16 [95% CI 1.10-1.23] and HR: 1.22 [95%CI 1.15-1.30], respectively in subgroups with NCEP/ATP III and JIS criteria applied). Conclusions MetS is associated with increased all-cause mortality risk in non-obese and obese patients. In patients without MetS obesity remains significantly associated with mortality. The concept of metabolically healthy obesity should be revised